1st annual THRIVE meeting

The first annual meeting of THRIVE was held online on February 6, 2025, bringing together all Consortium partners, and members of the External Advisory Board.

The meeting provided an opportunity to review the project’s first-year achievements and discuss plans for the future. Innovation Acta facilitated the organization of the meeting and presented updates on project management, as well as dissemination and communication activities.

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Agenda


1st Understanding Cluster Meeting

The first annual meeting of the Understanding Cluster – Tumor-Host Interactions was succesfully organised in Barcelona on January 31, 2025, hosted by THRIVE and IDIBAPS. Innovation Acta played a key role in organizing the meeting and actively contributing to discussions on the key topics covered by the meeting.

This milestone event marked a key step in our collective mission to unravel the complexities of tumor-host interactions and drive innovation in cancer research. Representatives from all six projects within the Cluster (THRIVE, MULTIR, GLIOMATCH, ARTURO, SPACETIME) and the HaDEA Project Officer Marianne Da Silva came together for insightful discussions on critical topics, including:

 Data Management and Sharing
 Communication and Dissemination
 Research and Innovation
 Addressing Inequalities
 Citizen and Patient Engagement

Through inspiring keynotes, engaging panel discussions, and collaborative networking sessions, we explored new opportunities to accelerate progress and maximize the impact of our research. We look forward to building on this momentum and continuing our journey toward meaningful scientific advancements

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Agenda


Thrive at the EASL Congress 2024

From June 5 to 8, 2024, Milan, Italy, hosted the EASL Congress 2024, which stands out as Europe's largest event in hepatology. The congress attracted over 7,000 professionals, including clinicians, researchers, allied health professionals, patient representatives, and industry experts.

THRIVE had the opportunity to present the project, engage with professionals in the area, and disseminate our initial findings to the EASL attendees.

THRIVE Networking session:

Title: Networking Session: Thrive
Presenter: Roser Pinyol
Session-Type: Oral presentation
Topic: Liver Tumours
Date: Friday, 7 Jun, 10:00 – 10:30 CEST
THRIVE Partner(s): ALL

Oral Presentations:

Title: Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis (OS-103)
Presenter: Svenja Schuehle
Session-Type: Oral presentation
Topic: Basic Science
Date: Saturday, 8 Jun, 11:30 – 11:45 CEST
THRIVE Partner(s): Prof. Mathias Heikenwälder, Prof. Eran Elinav

Poster presentations:

Title: Semaglutide achieves resolution of metabolic dysfunction-associated steatohepatitis via modulation of multiple pathogenic pathways: insights from human and animal studies (LBP-003)
Presenter: Quentin M. Anstee
Session-Type: Poster
Topic: General Hepatology
Date: Wednesday, 5 Jun, from 08:30
THRIVE Partner(s): Prof. Quentin M Anstee

 

Title: Analyses of fibrosis biomarkers PRO-C3 and ELF in resmetirom treated patients from MAESTRO-NASH, a 52 Week NASH/MASH serial liver biopsy study (WED-196)
Presenter: Quentin M. Anstee
Session-Type: Poster
Topic: Metabolism, Alcohol and Toxicity
Date: Wednesday, 5 Jun, from 08:30
THRIVE Partner(s): Prof. Quentin M Anstee

 

Title: Single-cell RNA sequencing-derived gene signatures reveal distinct response mechanisms to atezolizumab + bevacizumab in advanced hepatocellular carcinoma (TOP-507-YI)
Presenter: Marta Piqué-Gili
Session-Type: Poster (EASL Best poster Award)
Topic: Liver Tumours; Basic Science
Date: Friday, 7 Jun from 08:30 CEST
THRIVE Partner(s): Prof. Josep M Llovet, Prof. Mathias Heikenwälder, Prof. Helen Reeves

 

Title: Efficacy of WNTinib, a novel selective therapeutic for CTNNB1 mutant tumors, in preclinical models of hepatoblastoma (FRI-467)
Presenter: Ugne Balaseviciute
Session-Type: Poster + Poster Tour
Topic: Liver Tumours; Basic Science
Date: Friday, 7 Jun from 08:30 CEST;
Tour on: Friday, 7 Jun, 13:17 – 13:25 CEST
THRIVE Partner(s): Prof. Josep M Llovet

Title: qBallooning: AI-based ballooned hepatocyte detection and quantification by second harmonic generation/two photon excitation microscopy (FRI-208)
Presenter: Dean Tai
Session-Type: Poster + Poster tour
Topic: Metabolism, Alcohol and Toxicity
Date: Friday, 7 Jun, from 08:30 CEST
Tour: Saturday, 8 Jun, 12:15 – 12:22 CEST
THRIVE Partner(s): Prof. Quentin M Anstee

 

Title: Implications and therapeutic potential of neddylation for pediatric liver cancer: hepatoblastoma
Presenter: Leidy Estefanía Zapata-Pavas
Session-Type: Poster
Topic: Liver Tumours; Basic Science
Date: Friday, 7 Jun from 08:30 CEST
THRIVE Partner(s): Dr. Carolina Armengol

 

Title: Oncogenic beta-catenin is using CD155 as a molecular actor to corrupt immunosurveillance of cold HCC (TOP-552).
Presenter: Joana Gonçalves Araujo
Session-Type: Poster (Top) + Poster tour
Topic: Basic Science
Date: Saturday, 8 Jun, from 08:30 CEST
Tour: Saturday, 8 Jun, 12:45 – 12:55 CEST
THRIVE Partner(s): Prof. Jessica Zucman-Rossi

Symposia, Workshops and Studios:

Title: Advances in systemic treatments in liver cancer
Presenters: Josep M Llovet, Jessica Zucman-Rossi, Massimo Iavarone and Matthias Pinter
Topic: Liver Tumours
Date: Wednesday, 5 Jun, 13:15 – 13:45 CEST
THRIVE Partner(s): Prof. Josep M Llovet, Prof. Jessica Zucman-Rossi

 

Title: Shaping scientific progress – Excellence in peer review and editorial decision making (Session): What’s behind the editor‘s decision: Work behind the scenes & performance metrics
Presenter: Jessica Zucman-Rossi
Topic: General Hepatology
Date: Thursday, 6 Jun, 15:00 – 15:10 CEST
THRIVE Partner(s): Prof. Jessica Zucman-Rossi

 

Title: FAIR principles. Workshop.
Presenter: Quentin M. Anstee
Topic: General Hepatology
Date: Thursday, 6 Jun, 17:05 – 17:20 CEST
THRIVE Partner(s): Prof. Quentin M Anstee

Title: JHep Reports: New team approach
Presenter: Josep M Llovet
Topic: General Hepatology
Date: Friday, 7 Jun, 15:00 – 16:00 CEST
THRIVE Partner(s): Prof. Josep M Llovet

 

Title: Tissue and circulating biomarkers for diagnosis and management of HCC and cholangiocarcinoma
Presenter: Jessica Zucma-Rossi (Chair), Stephanie Roessler (Chair), Valérie Paradis, Bruno Sangro, Jesús M. Bañales
Topic: Liver Tumours
Date: Saturday, 8 Jun, 08:30 – 09:45 CEST
THRIVE Partner(s): Prof. Jessica Zucman-Rossi


Thrive website is online

Welcome on new THRIVE Project website

Responsive website


Thrive Kick-Off Meeting

The European Union’s THRIVE project (Tumor host interactions in liver cancer for childhood and adults) held its kick-off meeting on Friday, 12 January 2024. Thirty-five people attended the meeting, which took place in the Esteve Auditorium of the Esther Koplowitz Centre, where IDIBAPS’ headquarters are located.